Cancer reversion is the biological process by which tumorigenic cells lose all, or a significant part of, their malignant phenotype. The objective of this project is to develop and apply novel computational systems biology tools to identify molecular drivers of cancer reversion, their mechanisms of action and their clinical application.
Cancer Reversion: Computational Systems Biology Approaches
Lauren Marazzi, Andrew Gainer-Dewar, Paola Vera-Licona †. OCSANA+: optimal control and simulation of signaling networks from network analysis. 2019.
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